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Molecular models of multiple sclerosis severity identify heterogeneity of pathogenic mechanisms

While autopsy studies identify many abnormalities in the central nervous system (CNS) of subjects dying with neurological diseases, without their quantification in living subjects across the lifespan, pathogenic processes cannot be differentiated from epiphenomena. Using machine learning (ML), we se...

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Detalles Bibliográficos
Autores principales: Kosa, Peter, Barbour, Christopher, Varosanec, Mihael, Wichman, Alison, Sandford, Mary, Greenwood, Mark, Bielekova, Bibiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744737/
https://www.ncbi.nlm.nih.gov/pubmed/36509784
http://dx.doi.org/10.1038/s41467-022-35357-4