Valproic acid exposure decreases neurogenic potential of outer radial glia in human brain organoids

Valproic acid (VPA) exposure during pregnancy leads to a higher risk of autism spectrum disorder (ASD) susceptibility in offspring. Human dorsal forebrain organoids were used to recapitulate course of cortical neurogenesis in the developing human brain. Combining morphological characterization with...

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Detalles Bibliográficos
Autores principales: Zang, Zhenle, Yin, Huachun, Du, Zhulin, Xie, Ruxin, Yang, Ling, Cai, Yun, Wang, Liuyongwei, Zhang, Dandan, Li, Xin, Liu, Tianyao, Gong, Hong, Gao, Junwei, Yang, Hui, Warner, Margaret, Gustafsson, Jan-Ake, Xu, Haiwei, Fan, Xiaotang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744776/
https://www.ncbi.nlm.nih.gov/pubmed/36523605
http://dx.doi.org/10.3389/fnmol.2022.1023765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744776/
https://www.ncbi.nlm.nih.gov/pubmed/36523605
http://dx.doi.org/10.3389/fnmol.2022.1023765

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