Cargando…

Valproic acid exposure decreases neurogenic potential of outer radial glia in human brain organoids

Valproic acid (VPA) exposure during pregnancy leads to a higher risk of autism spectrum disorder (ASD) susceptibility in offspring. Human dorsal forebrain organoids were used to recapitulate course of cortical neurogenesis in the developing human brain. Combining morphological characterization with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zang, Zhenle, Yin, Huachun, Du, Zhulin, Xie, Ruxin, Yang, Ling, Cai, Yun, Wang, Liuyongwei, Zhang, Dandan, Li, Xin, Liu, Tianyao, Gong, Hong, Gao, Junwei, Yang, Hui, Warner, Margaret, Gustafsson, Jan-Ake, Xu, Haiwei, Fan, Xiaotang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744776/ https://www.ncbi.nlm.nih.gov/pubmed/36523605 http://dx.doi.org/10.3389/fnmol.2022.1023765

Ejemplares similares

Female mice lacking ERβ display excitatory/inhibitory synaptic imbalance to drive the pathogenesis of temporal lobe epilepsy
por: Wang, Zhongke, et al.
Publicado: (2021)

Neuronal Delamination and Outer Radial Glia Generation in Neocortical Development
por: Kawaguchi, Ayano
Publicado: (2021)

Secretoneurin A regulates neurogenic and inflammatory transcriptional networks in goldfish (Carassius auratus) radial glia
por: Da Fonte, Dillon F., et al.
Publicado: (2017)

Radial glia and radial glia-like cells: Their role in neurogenesis and regeneration
por: Miranda-Negrón, Yamil, et al.
Publicado: (2022)

Estrogen receptor β deficiency impairs gut microbiota: a possible mechanism of IBD-induced anxiety-like behavior
por: Ma, Yuanyuan, et al.
Publicado: (2022)

mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex
por: Andrews, Madeline G, et al.
Publicado: (2020)

Forebrain Organoids to Model the Cell Biology of Basal Radial Glia in Neurodevelopmental Disorders and Brain Evolution
por: Kaluthantrige Don, Flaminia, et al.
Publicado: (2022)

Unlocking the Neurogenic Potential of Mammalian Müller Glia
por: Xia, Xiaohuan, et al.
Publicado: (2016)

Development, Diversity, and Neurogenic Capacity of Enteric Glia
por: Boesmans, Werend, et al.
Publicado: (2022)

Human brain organoid model of maternal immune activation identifies radial glia cells as selectively vulnerable
por: Sarieva, Kseniia, et al.
Publicado: (2023)

Regenerative neurogenic response from glia requires insulin-driven neuron-glia communication
por: Harrison, Neale J, et al.
Publicado: (2021)

A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding
por: Wang, Lei, et al.
Publicado: (2022)

Sonic hedgehog signaling: A conserved mechanism for the expansion of outer radial glia and intermediate progenitor cells and for the growth and folding of the neocortex
por: Han, Young-Goo
Publicado: (2016)

Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia
por: Heng, Xin, et al.
Publicado: (2017)

Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia
por: Rakotomamonjy, Jennifer, et al.
Publicado: (2017)

Mechanisms of radial glia progenitor cell lineage progression
por: Beattie, Robert, et al.
Publicado: (2017)

Boundary Caps Give Rise to Neurogenic Stem Cells and Terminal Glia in the Skin
por: Gresset, Aurélie, et al.
Publicado: (2015)

A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia
por: Laddach, Anna, et al.
Publicado: (2023)

Identification of Radial Glia Progenitors in the Developing and Adult Retina of Sharks
por: Sánchez-Farías, Nuria, et al.
Publicado: (2016)

Adult Human Glioblastomas Harbor Radial Glia-like Cells
por: Wang, Rong, et al.
Publicado: (2020)

Assessment of radial glia in the frontal lobe of fetuses with Down syndrome
por: Baburamani, Ana A., et al.
Publicado: (2020)

Adult Human Glioblastomas Harbor Radial Glia-like Cells
por: Wang, Rong, et al.
Publicado: (2020)

Radial glia require PDGFD/PDGFRß signaling in human but not mouse neocortex
por: Lui, Jan H., et al.
Publicado: (2014)

Radial glia regulate vascular patterning around the developing spinal cord
por: Matsuoka, Ryota L, et al.
Publicado: (2016)

Developmental and functional relationships between hypothalamic tanycytes and embryonic radial glia
por: Fong, Harmony, et al.
Publicado: (2023)

Echinoderm radial glia in adult cell renewal, indeterminate growth, and regeneration
por: Mashanov, Vladimir, et al.
Publicado: (2023)

Adult Spinal Cord Radial Glia Display a Unique Progenitor Phenotype
por: Petit, Audrey, et al.
Publicado: (2011)

Radial glia interact with primary olfactory axons to regulate development of the olfactory bulb
por: Amaya, Daniel A., et al.
Publicado: (2015)

Extracellular Control of Radial Glia Proliferation and Scaffolding During Cortical Development and Pathology
por: Ferent, Julien, et al.
Publicado: (2020)

Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
por: Bilgic, Merve, et al.
Publicado: (2023)

Human forebrain organoids reveal connections between valproic acid exposure and autism risk
por: Meng, Qingtuan, et al.
Publicado: (2022)

Network Reconstruction Reveals that Valproic Acid Activates Neurogenic Transcriptional Programs in Adult Brain Following Traumatic Injury
por: Higgins, Gerald A., et al.
Publicado: (2017)

Transcriptional Signature of Valproic Acid-Induced Neural Tube Defects in Human Spinal Cord Organoids
por: Lee, Ju-Hyun, et al.
Publicado: (2023)

Loss of functional Dicer in mouse radial glia cell-autonomously prolongs cortical neurogenesis()
por: Nowakowski, Tomasz Jan, et al.
Publicado: (2013)

TGF-β1 promotes cerebral cortex radial glia-astrocyte differentiation in vivo
por: Stipursky, Joice, et al.
Publicado: (2014)

Radial glia in the proliferative ventricular zone of the embryonic and adult turtle, Trachemys scripta elegans
por: Clinton, Brian K, et al.
Publicado: (2014)

Ttc21b Is Required in Bergmann Glia for Proper Granule Cell Radial Migration
por: Driver, Ashley M., et al.
Publicado: (2017)

Jak/Stat signaling regulates the proliferation and neurogenic potential of Müller glia-derived progenitor cells in the avian retina
por: Todd, Levi, et al.
Publicado: (2016)

A multiplexed, single-cell sequencing screen identifies compounds that increase neurogenic reprogramming of murine Muller glia
por: Tresenrider, Amy, et al.
Publicado: (2023)

AAV Delivery of shRNA Against TRPC6 in Mouse Hippocampus Impairs Cognitive Function
por: Xie, Ruxin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ccsgjjkq1401k728krrc7c2t4n