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Analysis of the safety and efficacy of different plasma concentrations of pirfenidone in patients with idiopathic pulmonary fibrosis

The high incidence and mortality of idiopathic pulmonary fibrosis (IPF) have led to the widespread use of antifibrotic drugs such as pirfenidone; however, the associated adverse reactions greatly vary among individuals and the dose is not fixed. To date, no reliable blood concentration range of pirf...

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Detalles Bibliográficos
Autores principales: Li, Hui, Yang, Jing, Chen, Shanshan, Wang, Peile, Yu, Xueqing, Zhou, Qingwei, Zhang, Xiaojian, Zhang, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744780/
https://www.ncbi.nlm.nih.gov/pubmed/36523502
http://dx.doi.org/10.3389/fphar.2022.1055702