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New models of Parkinson’s like neuroinflammation in human microglia clone 3: Activation profiles induced by INF-γ plus high glucose and mitochondrial inhibitors

Microglia activation and neuroinflammation have been extensively studied in murine models of neurodegenerative diseases; however, to overcome the genetic differences between species, a human cell model of microglia able to recapitulate the activation profiles described in patients is needed. Here we...

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Detalles Bibliográficos
Autores principales: De Chirico, Francesca, Poeta, Eleonora, Babini, Giorgia, Piccolino, Iliana, Monti, Barbara, Massenzio, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744797/
https://www.ncbi.nlm.nih.gov/pubmed/36523814
http://dx.doi.org/10.3389/fncel.2022.1038721