Broad misappropriation of developmental splicing profile by cancer in multiple organs

Oncogenesis mimics key aspects of embryonic development. However, the underlying mechanisms are incompletely understood. Here, we demonstrate that the splicing events specifically active during human organogenesis, are broadly reactivated in the organ-specific tumor. Such events are associated with...

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Detalles Bibliográficos
Autores principales: Singh, Arashdeep, Rajeevan, Arati, Gopalan, Vishaka, Agrawal, Piyush, Day, Chi-Ping, Hannenhalli, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744839/
https://www.ncbi.nlm.nih.gov/pubmed/36509773
http://dx.doi.org/10.1038/s41467-022-35322-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744839/
https://www.ncbi.nlm.nih.gov/pubmed/36509773
http://dx.doi.org/10.1038/s41467-022-35322-1

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