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Galleria mellonella immune melanization is fungicidal during infection

A key component of the insect immune response is melanin production, including within nodules, or aggregations of immune cells surrounding microbes. Melanization produces oxidative and toxic intermediates that limit microbial infections. However, a direct fungicidal role of melanin during infection...

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Detalles Bibliográficos
Autores principales: Smith, Daniel F. Q., Dragotakes, Quigly, Kulkarni, Madhura, Hardwick, J. Marie, Casadevall, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744840/
https://www.ncbi.nlm.nih.gov/pubmed/36510005
http://dx.doi.org/10.1038/s42003-022-04340-6