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Current progress and open challenges for applying tyrosine kinase inhibitors in osteosarcoma

Osteosarcoma (OS) is a mesenchymal-origin tumor that constitutes the most common primary malignant bone tumor. The survival rate of the patients has significantly improved since the introduction of neoadjuvant chemotherapy and extensive resection, but it has stagnated in recent 40 years. Tyrosine ki...

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Detalles Bibliográficos
Autores principales: Chen, Chenglong, Shi, Qianyu, Xu, Jiuhui, Ren, Tingting, Huang, Yi, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744866/
https://www.ncbi.nlm.nih.gov/pubmed/36509754
http://dx.doi.org/10.1038/s41420-022-01252-6