Disruption of male fertility-critical Dcaf17 dysregulates mouse testis transcriptome

During mammalian spermatogenesis, the ubiquitin proteasome system maintains protein homoeostasis (proteastasis) and spermatogenic cellular functions. DCAF17 is a substrate receptor in the ubiquitin CRL4 E3 Ligase complex, absence of which causes oligoasthenoteratozoospermia in mice resulting in male...

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Detalles Bibliográficos
Autores principales: Abu-Dawud, Raed, Mistry, Bhavesh V., Rajab, Mohamed, Alanazi, Maha, Al-Yacoub, Nadya, Kashir, Junaid, Almohanna, Falah, Colak, Dilek, Assiri, Abdullah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744869/
https://www.ncbi.nlm.nih.gov/pubmed/36509865
http://dx.doi.org/10.1038/s41598-022-25826-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744869/
https://www.ncbi.nlm.nih.gov/pubmed/36509865
http://dx.doi.org/10.1038/s41598-022-25826-7

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