Pseudomonas aeruginosa aggregation and Psl expression in sputum is associated with antibiotic eradication failure in children with cystic fibrosis

We previously demonstrated that P. aeruginosa isolates that persisted in children with cystic fibrosis (CF) despite inhaled tobramycin treatment had increased anti-Psl antibody binding in vitro compared to those successfully eradicated. We aimed to validate these findings by directly visualizing P....

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Detalles Bibliográficos
Autores principales: Morris, Amanda J., Yau, Yvonne C. W., Park, Subin, Eisha, Shafinaz, McDonald, Nancy, Parsek, Matthew R., Howell, P. Lynne, Hoffman, Lucas R., Nguyen, Dao, DiGiandomenico, Antonio, Rooney, Ashley M., Coburn, Bryan, Grana-Miraglia, Lucia, Wang, Pauline, Guttman, David S., Wozniak, Daniel J., Waters, Valerie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744911/
https://www.ncbi.nlm.nih.gov/pubmed/36509824
http://dx.doi.org/10.1038/s41598-022-25889-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744911/
https://www.ncbi.nlm.nih.gov/pubmed/36509824
http://dx.doi.org/10.1038/s41598-022-25889-6

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