Intranasal inoculation of IFN-λ resolves SARS-CoV-2 lung infection via the rapid reduction of viral burden and improvement of tissue damage

INTRODUCTION: The innate immune responses of upper airway could further our understanding toward antiviral strategies against SARS-CoV-2. We characterize the potential of interferon (IFN)-λ as an innate immune inducer for the rapid clearance of SARS-CoV-2 in the lung and the therapeutic efficacy of...

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Detalles Bibliográficos
Autores principales: Shin, Haeun, Kim, Sujin, Jo, Ara, Won, Jina, Gil, Chan Hee, Yoon, So Yeon, Cha, Hyunkyung, Kim, Hyun Jik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744928/
https://www.ncbi.nlm.nih.gov/pubmed/36524125
http://dx.doi.org/10.3389/fimmu.2022.1009424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744928/
https://www.ncbi.nlm.nih.gov/pubmed/36524125
http://dx.doi.org/10.3389/fimmu.2022.1009424

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