Sperm-carried IGF2 downregulated the expression of mitogens produced by Sertoli cells: A paracrine mechanism for regulating spermatogenesis?

INTRODUCTION: Insulin-like growth factor 2 (IGF2) mRNA has been found in human and mouse spermatozoa. It is currently unknown whether the IGF2 protein is expressed in human spermatozoa and, if so, its possible role in the cross-talk between germ and Sertoli cells (SCs) during spermatogenesis. METHOD...

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Detalles Bibliográficos
Autores principales: Cannarella, Rossella, Mancuso, Francesca, Arato, Iva, Lilli, Cinzia, Bellucci, Catia, Gargaro, Marco, Curto, Roberto, Aglietti, Maria C., La Vignera, Sandro, Condorelli, Rosita A., Luca, Giovani, Calogero, Aldo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744929/
https://www.ncbi.nlm.nih.gov/pubmed/36523595
http://dx.doi.org/10.3389/fendo.2022.1010796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744929/
https://www.ncbi.nlm.nih.gov/pubmed/36523595
http://dx.doi.org/10.3389/fendo.2022.1010796

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