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Caspase-1 and the inflammasome promote polycystic kidney disease progression

We and others have previously shown that the presence of renal innate immune cells can promote polycystic kidney disease (PKD) progression. In this study, we examined the influence of the inflammasome, a key part of the innate immune system, on PKD. The inflammasome is a system of molecular sensors,...

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Detalles Bibliográficos
Autores principales: Swenson-Fields, Katherine I., Ward, Christopher J., Lopez, Micaila E., Fross, Shaneann, Heimes Dillon, Anna L., Meisenheimer, James D., Rabbani, Adib J., Wedlock, Emily, Basu, Malay K., Jansson, Kyle P., Rowe, Peter S., Stubbs, Jason R., Wallace, Darren P., Vitek, Michael P., Fields, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745047/
https://www.ncbi.nlm.nih.gov/pubmed/36523654
http://dx.doi.org/10.3389/fmolb.2022.971219