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Caspase-1 and the inflammasome promote polycystic kidney disease progression
We and others have previously shown that the presence of renal innate immune cells can promote polycystic kidney disease (PKD) progression. In this study, we examined the influence of the inflammasome, a key part of the innate immune system, on PKD. The inflammasome is a system of molecular sensors,...
Autores principales: | Swenson-Fields, Katherine I., Ward, Christopher J., Lopez, Micaila E., Fross, Shaneann, Heimes Dillon, Anna L., Meisenheimer, James D., Rabbani, Adib J., Wedlock, Emily, Basu, Malay K., Jansson, Kyle P., Rowe, Peter S., Stubbs, Jason R., Wallace, Darren P., Vitek, Michael P., Fields, Timothy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745047/ https://www.ncbi.nlm.nih.gov/pubmed/36523654 http://dx.doi.org/10.3389/fmolb.2022.971219 |
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