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Detection of differentially expressed genes in spatial transcriptomics data by spatial analysis of spatial transcriptomics: A novel method based on spatial statistics

BACKGROUND: Spatial transcriptomics (STs) simultaneously obtains the location and amount of gene expression within a tissue section. However, current methods like FindMarkers calculated the differentially expressed genes (DEGs) based on the classical statistics, which should abolish the spatial info...

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Detalles Bibliográficos
Autores principales: Qiu, Zhihua, Li, Shaojun, Luo, Ming, Zhu, Shuanggen, Wang, Zhijian, Jiang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745188/
https://www.ncbi.nlm.nih.gov/pubmed/36523429
http://dx.doi.org/10.3389/fnins.2022.1086168