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Knockdown of Nrf2 radiosensitizes glioma cells by inducing redox stress and apoptosis in hypoxia

BACKGROUND: Radiotherapy remains a mainstream treatment for patients with glioma. Yet intrinsic radioresistance has largely compromised the efficacy of the treatment. Increasing concerns have been raised that overexpression of the Nrf2, along with a hypoxic tumor microenvironment, may have contribut...

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Detalles Bibliográficos
Autores principales: Tang, Ting, Jia, Yue, Liang, Hui, Han, Yanling, Cong, Zixiang, Wang, Handong, Ji, Xiangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745379/
https://www.ncbi.nlm.nih.gov/pubmed/36523295
http://dx.doi.org/10.21037/tcr-22-1420