Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells

BACKGROUND: Fibro‐adipogenic progenitors (FAPs) in the muscles have been found to interact closely with muscle progenitor/stem cells (MPCs) and facilitate muscle regeneration at normal conditions. However, it is not clear how FAPs may interact with MPCs in aged muscles. Senolytics have been demonstr...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Yue, Xianlin, Sun, Zewei, Hambright, William S., Wei, Jianming, Li, Ying, Matre, Polina, Cui, Yan, Wang, Zhihui, Rodney, George, Huard, Johnny, Robbins, Paul D., Mu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745459/
https://www.ncbi.nlm.nih.gov/pubmed/36218080
http://dx.doi.org/10.1002/jcsm.13101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745459/
https://www.ncbi.nlm.nih.gov/pubmed/36218080
http://dx.doi.org/10.1002/jcsm.13101

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