Stable HIV Reservoir Despite Prolonged Low-Dose Mycophenolate to Limit CD4+ T-cell Proliferation

BACKGROUND: The HIV reservoir of latently infected CD4+ T cells represents the barrier to cure. CD4+ T-cell proliferation is a mechanism that sustains the reservoir even during prolonged antiretroviral therapy (ART). Blocking proliferation may therefore deplete the reservoir. METHODS: We conducted a...

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Detalles Bibliográficos
Autores principales: Schiffer, Joshua T, Levy, Claire, Hughes, Sean M, Pandey, Urvashi, Padullo, Mel, Jerome, Keith R, Zhu, Haiying, Puckett, Katrina, Helgeson, Eric, Harrington, Robert D, Hladik, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745781/
https://www.ncbi.nlm.nih.gov/pubmed/36519118
http://dx.doi.org/10.1093/ofid/ofac620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745781/
https://www.ncbi.nlm.nih.gov/pubmed/36519118
http://dx.doi.org/10.1093/ofid/ofac620

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