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A General Catalyst Controlled Route to Prostaglandin F2(α)

[Image: see text] We report a general, catalyst-controlled route to prostaglandin F2(α) and its analogues. The approach uses a Rh-catalyzed dynamic kinetic asymmetric Suzuki–Miyaura coupling reaction between a racemic bicyclic allyl chloride and alkenyl boronic esters bearing chiral alcohols to give...

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Detalles Bibliográficos
Autores principales: Cunningham, Laura, Mishra, Sourabh, Matthews, Leon, Fletcher, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745796/
https://www.ncbi.nlm.nih.gov/pubmed/36446080
http://dx.doi.org/10.1021/acs.orglett.2c03718