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A General Catalyst Controlled Route to Prostaglandin F2(α)
[Image: see text] We report a general, catalyst-controlled route to prostaglandin F2(α) and its analogues. The approach uses a Rh-catalyzed dynamic kinetic asymmetric Suzuki–Miyaura coupling reaction between a racemic bicyclic allyl chloride and alkenyl boronic esters bearing chiral alcohols to give...
Autores principales: | Cunningham, Laura, Mishra, Sourabh, Matthews, Leon, Fletcher, Stephen P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745796/ https://www.ncbi.nlm.nih.gov/pubmed/36446080 http://dx.doi.org/10.1021/acs.orglett.2c03718 |
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