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Insights into the Spectrum of Activity and Mechanism of Action of MGB-BP-3
[Image: see text] MGB-BP-3 is a potential first-in-class antibiotic, a Strathclyde Minor Groove Binder (S-MGB), that has successfully completed Phase IIa clinical trials for the treatment of Clostridioides difficile associated disease. Its precise mechanism of action and the origin of limited activi...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745797/ https://www.ncbi.nlm.nih.gov/pubmed/36444998 http://dx.doi.org/10.1021/acsinfecdis.2c00445 |