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Polymyxin Stereochemistry and Its Role in Antibacterial Activity and Outer Membrane Disruption

[Image: see text] With increasing rates of resistance toward commonly used antibiotics, especially among Gram-negative bacteria, there is renewed interested in polymyxins. Polymyxins are lipopeptide antibiotics with potent anti-Gram-negative activity and are generally believed to target lipid A, the...

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Detalles Bibliográficos
Autores principales: Slingerland, Cornelis J., Kotsogianni, Ioli, Wesseling, Charlotte M. J., Martin, Nathaniel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745799/
https://www.ncbi.nlm.nih.gov/pubmed/36342383
http://dx.doi.org/10.1021/acsinfecdis.2c00307