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Polymyxin Stereochemistry and Its Role in Antibacterial Activity and Outer Membrane Disruption
[Image: see text] With increasing rates of resistance toward commonly used antibiotics, especially among Gram-negative bacteria, there is renewed interested in polymyxins. Polymyxins are lipopeptide antibiotics with potent anti-Gram-negative activity and are generally believed to target lipid A, the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745799/ https://www.ncbi.nlm.nih.gov/pubmed/36342383 http://dx.doi.org/10.1021/acsinfecdis.2c00307 |