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Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF
The polyadenylation signal (PAS) is a key sequence element for 3′-end cleavage and polyadenylation of messenger RNA precursors (pre-mRNAs). This hexanucleotide motif is recognized by the mammalian polyadenylation specificity factor (mPSF), consisting of CPSF160, WDR33, CPSF30, and Fip1 subunits. Rec...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745836/ https://www.ncbi.nlm.nih.gov/pubmed/36130077 http://dx.doi.org/10.1261/rna.079322.122 |