Structures of RNA ligase RtcB in complexes with divalent cations and GTP

Pyrococcus horikoshii (Pho) RtcB exemplifies a family of binuclear transition metal- and GTP-dependent RNA ligases that join 3′-phosphate and 5′-OH ends via RtcB-(histidinyl-N)–GMP and RNA(3')pp(5')G intermediates. We find that guanylylation of PhoRtcB is optimal with manganese and less ef...

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Detalles Bibliográficos
Autores principales: Jacewicz, Agata, Dantuluri, Swathi, Shuman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745838/
https://www.ncbi.nlm.nih.gov/pubmed/36130078
http://dx.doi.org/10.1261/rna.079327.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745838/
https://www.ncbi.nlm.nih.gov/pubmed/36130078
http://dx.doi.org/10.1261/rna.079327.122

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