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EIF3B stabilizes PTGS2 expression by counteracting MDM2‐mediated ubiquitination to promote the development and progression of malignant melanoma

Malignant melanoma (MM) is a neoplasm that develops from human melanocytes. It was reported that eukaryotic translation initiation factor 3 subunit B (EIF3B) is associated with multiple types of cancers, but its role in MM has not been reported. In the present study, we found that EIF3B was abundant...

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Detalles Bibliográficos
Autores principales: Fang, Pengli, Han, Yikai, Qu, Yanhong, Wang, Xin, Zhang, Yong, Zhang, Wei, Zhang, Na, Li, Guangshuai, Ma, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746036/
https://www.ncbi.nlm.nih.gov/pubmed/36050601
http://dx.doi.org/10.1111/cas.15543