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Cancerous pH‐responsive polycarboxybetaine‐coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model in mice

Lipid nanoparticles (LNPs) have been commonly used as a vehicle for nucleic acids, such as small interfering RNA (siRNA); the surface modification of LNPs is one of the determinants of their delivery efficiency especially in systemic administration. However, the applications of siRNA‐encapsulated LN...

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Detalles Bibliográficos
Autores principales: Sung, Yi‐Jung, Guo, Haochen, Ghasemizadeh, Aria, Shen, Xin, Chintrakulchai, Wanphiwat, Kobayashi, Motoaki, Toyoda, Masahiro, Ogi, Koichi, Michinishi, Junya, Ohtake, Tomoyuki, Matsui, Makoto, Honda, Yuto, Nomoto, Takahiro, Takemoto, Hiroyasu, Miura, Yutaka, Nishiyama, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746038/
https://www.ncbi.nlm.nih.gov/pubmed/36047963
http://dx.doi.org/10.1111/cas.15554