Cargando…
Cancerous pH‐responsive polycarboxybetaine‐coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model in mice
Lipid nanoparticles (LNPs) have been commonly used as a vehicle for nucleic acids, such as small interfering RNA (siRNA); the surface modification of LNPs is one of the determinants of their delivery efficiency especially in systemic administration. However, the applications of siRNA‐encapsulated LN...
Autores principales: | Sung, Yi‐Jung, Guo, Haochen, Ghasemizadeh, Aria, Shen, Xin, Chintrakulchai, Wanphiwat, Kobayashi, Motoaki, Toyoda, Masahiro, Ogi, Koichi, Michinishi, Junya, Ohtake, Tomoyuki, Matsui, Makoto, Honda, Yuto, Nomoto, Takahiro, Takemoto, Hiroyasu, Miura, Yutaka, Nishiyama, Nobuhiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746038/ https://www.ncbi.nlm.nih.gov/pubmed/36047963 http://dx.doi.org/10.1111/cas.15554 |
Ejemplares similares
-
Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism
por: Yamada, Naoki, et al.
Publicado: (2017) -
Polycarboxybetaine-Based Hydrogels for the Capture and Release of Circulating Tumor Cells
por: Chien, Hsiu-Wen, et al.
Publicado: (2022) -
Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine
por: Komoto, Kana, et al.
Publicado: (2020) -
Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers
por: Dou, Xuebo, et al.
Publicado: (2018) -
Charge-switchable zwitterionic polycarboxybetaine particle as an intestinal permeation enhancer for efficient oral insulin delivery
por: Li, Yan, et al.
Publicado: (2021)