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BRCA1 transports the DNA damage signal for CDDP‐induced centrosome amplification through the centrosomal Aurora A

Breast cancer gene 1 (BRCA1) plays roles in DNA repair and centrosome regulation and is involved in DNA damage‐induced centrosome amplification (DDICA). Here, the centrosomal localization of BRCA1 and the kinases involved in centrosome duplication were analyzed in each cell cycle phase after treatme...

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Detalles Bibliográficos
Autores principales: Qi, Huicheng, Kikuchi, Megumi, Yoshino, Yuki, Fang, Zhenzhou, Ohashi, Kazune, Gotoh, Takato, Ideta, Ryo, Ui, Ayako, Endo, Shino, Otsuka, Kei, Shindo, Norihisa, Gonda, Kohsuke, Ishioka, Chikashi, Miki, Yoshio, Iwabuchi, Tokuro, Chiba, Natsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746055/
https://www.ncbi.nlm.nih.gov/pubmed/36082621
http://dx.doi.org/10.1111/cas.15573