Kinin B1 receptor blockade attenuates hepatic fibrosis and portal hypertension in chronic liver diseases in mice

BACKGROUND AND AIMS: Kinin B1 receptors (B1Rs) are implicated in the pathogenesis of fibrosis. This study examined the anti-fibrotic effects of B1R blockade with BI 113823 in two established mouse models of hepatic fibrosis induced by intraperitoneal carbon tetrachloride (CCl(4)) injection or bile d...

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Detalles Bibliográficos
Autores principales: Rampa, Dileep Reddy, Feng, Huiying, Allur-Subramaniyan, Sivakumar, Shim, Kwanseob, Pekcec, Anton, Lee, Dongwon, Doods, Henri, Wu, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746183/
https://www.ncbi.nlm.nih.gov/pubmed/36514072
http://dx.doi.org/10.1186/s12967-022-03808-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746183/
https://www.ncbi.nlm.nih.gov/pubmed/36514072
http://dx.doi.org/10.1186/s12967-022-03808-7

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