Comprehensive genomic profiling of a unique liposarcoma arising in a patient with Li–Fraumeni syndrome and the novel detection of c-myc amplification: a case report

BACKGROUND: Germline TP53 mutations have been frequently reported in patients with Li–Fraumeni syndrome (LFS), resulting in a predisposition to various malignancies. Mutations other than germline TP53 mutations can also cause LFS-associated malignancies, but their details remain unclear. We describe...

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Detalles Bibliográficos
Autores principales: Watanabe, Hirofumi, Fujishima, Fumiyoshi, Motoi, Toru, Aoyama, Yayoi, Niihori, Tetsuya, Takahashi, Masanobu, Umegaki, Sho, Oishi, Hisashi, Tada, Hiroshi, Ichinohasama, Ryo, Sasano, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746193/
https://www.ncbi.nlm.nih.gov/pubmed/36514176
http://dx.doi.org/10.1186/s13000-022-01264-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746193/
https://www.ncbi.nlm.nih.gov/pubmed/36514176
http://dx.doi.org/10.1186/s13000-022-01264-x

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