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Oleic acid from cancer-associated fibroblast promotes cancer cell stemness by stearoyl-CoA desaturase under glucose-deficient condition

BACKGROUND: Cancer-associated fibroblasts (CAFs) coordinate the malignancy of cancer cells via secretory materials. Reprogrammed lipid metabolism and signaling play critical roles in cancer biology. Oleic acid (OA) serves as a source of energy under glucose-deficient conditions, but its function in...

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Detalles Bibliográficos
Autores principales: Hwang, Sung-Hyun, Yang, Yeseul, Jung, Jae-Ha, Kim, Yongbaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746202/
https://www.ncbi.nlm.nih.gov/pubmed/36514170
http://dx.doi.org/10.1186/s12935-022-02824-3