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CCAAT/Enhancer-binding Protein Homologous Protein Promotes ROS-mediated Liver Ischemia and Reperfusion Injury by Inhibiting Mitophagy in Hepatocytes

Liver ischemia and reperfusion (IR) injury represent a major risk factor in both partial hepatectomy and liver transplantation. CCAAT/enhancer-binding protein homologous protein (CHOP) is a key regulator of cell death, its precise molecular basis in regulating hepatocyte death during liver IR has no...

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Detalles Bibliográficos
Autores principales: Zhou, Shun, Rao, Zhuqing, Xia, Yongxiang, Wang, Qi, Liu, Zheng, Wang, Ping, Cheng, Feng, Zhou, Haoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746334/
https://www.ncbi.nlm.nih.gov/pubmed/35821597
http://dx.doi.org/10.1097/TP.0000000000004244