Do Treg Speed Up with CARs? Chimeric Antigen Receptor Treg Engineered to Induce Transplant Tolerance

Adoptive transfer of regulatory T cells (Treg) can induce transplant tolerance in preclinical models by suppressing alloantigen-directed inflammatory responses; clinical translation was so far hampered by the low abundance of Treg with allo-specificity in the peripheral blood. In this situation, ex...

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Detalles Bibliográficos
Autores principales: Kaljanac, Marcell, Abken, Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746345/
https://www.ncbi.nlm.nih.gov/pubmed/36226849
http://dx.doi.org/10.1097/TP.0000000000004316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746345/
https://www.ncbi.nlm.nih.gov/pubmed/36226849
http://dx.doi.org/10.1097/TP.0000000000004316

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