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Intravenous injection of a novel viral immunotherapy encoding human interleukin-7 in nonhuman primates is safe and increases absolute lymphocyte count

Persistence of an immunosuppression, affecting both the innate and adaptive arms of the immune system, plays a role in sepsis patients’ morbidity and late mortality pointing to the need for broad and effective immune interventions. MVA-hIL-7-Fc is a non-replicative recombinant Modified Vaccinia viru...

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Detalles Bibliográficos
Autores principales: Coupet, Charles-Antoine, Dubois, Clarisse, Evlachev, Alexeï, Kehrer, Nadine, Baldazza, Marie, Hofman, Sam, Vierboom, Michel, Martin, Perrine, Inchauspe, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746448/
https://www.ncbi.nlm.nih.gov/pubmed/36315906
http://dx.doi.org/10.1080/21645515.2022.2133914