Generation and functional characterization of a multigene-modified NK101 cell line exerting diverse mechanisms of antitumor action

Clonal cell line-based, multigene-modified, off-the-shelf NK cell therapeutics are emerging as the new frontier of adoptive cellular immunotherapy. Here, we utilized a newly established NK cell line, NK101, as a backbone to derive multifaceted killer cells armored with various antitumor modalities t...

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Detalles Bibliográficos
Autores principales: Hwang, Injung, Jin, Hyun Tak, Kang, Moon Cheol, Kim, Tae Yoon, Sung, Young Chul, Kim, Sae Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746629/
https://www.ncbi.nlm.nih.gov/pubmed/36524207
http://dx.doi.org/10.1080/2162402X.2021.2014655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746629/
https://www.ncbi.nlm.nih.gov/pubmed/36524207
http://dx.doi.org/10.1080/2162402X.2021.2014655

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