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Generation and functional characterization of a multigene-modified NK101 cell line exerting diverse mechanisms of antitumor action
Clonal cell line-based, multigene-modified, off-the-shelf NK cell therapeutics are emerging as the new frontier of adoptive cellular immunotherapy. Here, we utilized a newly established NK cell line, NK101, as a backbone to derive multifaceted killer cells armored with various antitumor modalities t...
Autores principales: | Hwang, Injung, Jin, Hyun Tak, Kang, Moon Cheol, Kim, Tae Yoon, Sung, Young Chul, Kim, Sae Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746629/ https://www.ncbi.nlm.nih.gov/pubmed/36524207 http://dx.doi.org/10.1080/2162402X.2021.2014655 |
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