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An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature

Introduction: Several neurodegenerative conditions are associated with a common histopathology within neurons of the central nervous system, consisting of the deposition of cytoplasmic inclusions of TAR DNA-binding protein 43 (TDP-43). Such inclusions have variably been described as morphologically...

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Detalles Bibliográficos
Autores principales: Cascella, Roberta, Banchelli, Martina, Abolghasem Ghadami, Seyyed, Ami, Diletta, Gagliani, Maria Cristina, Bigi, Alessandra, Staderini, Tommaso, Tampellini, Davide, Cortese, Katia, Cecchi, Cristina, Natalello, Antonino, Adibi, Hadi, Matteini, Paolo, Chiti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746631/
https://www.ncbi.nlm.nih.gov/pubmed/36495262
http://dx.doi.org/10.1080/07853890.2022.2148734