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A Pilot Analysis of Genome‐Wide DNA Methylation Patterns in Mouse Cartilage Reveals Overlapping Epigenetic Signatures of Aging and Osteoarthritis

OBJECTIVE: Cartilage epigenetic changes are strongly associated with human osteoarthritis (OA). However, the influence of individual environmental OA risk factors on these epigenetic patterns has not been determined; herein we characterize cartilage DNA methylation patterns associated with aging and...

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Detalles Bibliográficos
Autores principales: Izda, Vladislav, Dunn, Christopher M., Prinz, Emmaline, Schlupp, Leoni, Nguyen, Emily, Sturdy, Cassandra, Jeffries, Matlock A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746664/
https://www.ncbi.nlm.nih.gov/pubmed/36253145
http://dx.doi.org/10.1002/acr2.11506