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Polygenic coronary artery disease association with brain atrophy in the cognitively impaired

While a number of low-frequency genetic variants of large effect size have been shown to underlie both cardiovascular disease and dementia, recent studies have highlighted the importance of common genetic variants of small effect size, which, in aggregate, are embodied by a polygenic risk score. We...

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Detalles Bibliográficos
Autores principales: de Silva, Eric, Sudre, Carole H, Barnes, Josephine, Scelsi, Marzia A, Altmann, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746681/
https://www.ncbi.nlm.nih.gov/pubmed/36523268
http://dx.doi.org/10.1093/braincomms/fcac314