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Polygenic coronary artery disease association with brain atrophy in the cognitively impaired
While a number of low-frequency genetic variants of large effect size have been shown to underlie both cardiovascular disease and dementia, recent studies have highlighted the importance of common genetic variants of small effect size, which, in aggregate, are embodied by a polygenic risk score. We...
Autores principales: | de Silva, Eric, Sudre, Carole H, Barnes, Josephine, Scelsi, Marzia A, Altmann, Andre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746681/ https://www.ncbi.nlm.nih.gov/pubmed/36523268 http://dx.doi.org/10.1093/braincomms/fcac314 |
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