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Complement inhibition prevents glial nodal membrane injury in a GM1 antibody-mediated mouse model

The involvement of the complement pathway in Guillain–Barré syndrome pathogenesis has been demonstrated in both patient biosamples and animal models. One proposed mechanism is that anti-ganglioside antibodies mediate neural membrane injury through the activation of complement and the formation of me...

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Detalles Bibliográficos
Autores principales: Campbell, Clare I, McGonigal, Rhona, Barrie, Jennifer A, Delaere, Jolien, Bracke, Laura, Cunningham, Madeleine E, Yao, Denggao, Delahaye, Tim, Van de Walle, Inge, Willison, Hugh J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746686/
https://www.ncbi.nlm.nih.gov/pubmed/36523267
http://dx.doi.org/10.1093/braincomms/fcac306