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Aspartate α-decarboxylase a new therapeutic target in the fight against Helicobacter pylori infection

Effective eradication therapy for Helicobacter pylori is a worldwide demand. Aspartate α-decarboxylase (ADC) was reported as a drug target in H. pylori, in an in silico study, with malonic acid (MA) as its inhibitor. We evaluated eradicating H. pylori infection through ADC inhibition and the possibi...

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Detalles Bibliográficos
Autores principales: Ibrahim, Kareem A., Kashef, Mona T., Elkhamissy, Tharwat R., Ramadan, Mohammed A., Helmy, Omneya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746714/
https://www.ncbi.nlm.nih.gov/pubmed/36523828
http://dx.doi.org/10.3389/fmicb.2022.1019666