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A mAb against surface-expressed FSHR engineered to engage adaptive immunity for ovarian cancer immunotherapy
Despite advances in ovarian cancer (OC) therapy, recurrent OC remains a poor-prognosis disease. Because of the close interaction between OC cells and the tumor microenvironment (TME), it is important to develop strategies that target tumor cells and engage components of the TME. A major obstacle in...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746812/ https://www.ncbi.nlm.nih.gov/pubmed/36509287 http://dx.doi.org/10.1172/jci.insight.162553 |