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Liposomal UHRF1 siRNA shows lung fibrosis treatment potential through regulation of fibroblast activation

Pulmonary fibrosis is a chronic and progressive interstitial lung disease associated with the decay of pulmonary function, which leads to a fatal outcome. As an essential epigenetic regulator of DNA methylation, the involvement of ubiquitin-like containing PHD and RING finger domains 1 (UHRF1) in fi...

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Detalles Bibliográficos
Autores principales: Cheng, Demin, Wang, Yue, Li, Ziwei, Xiong, Haojie, Sun, Wenqing, Xi, Sichuan, Zhou, Siyun, Liu, Yi, Ni, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746815/
https://www.ncbi.nlm.nih.gov/pubmed/36166308
http://dx.doi.org/10.1172/jci.insight.162831