Activated cholesterol metabolism is integral for innate macrophage responses by amplifying Myd88 signaling

Recent studies have shown that cellular metabolism is tightly linked to the regulation of immune cells. Here, we show that activation of cholesterol metabolism, involving cholesterol uptake, synthesis, and autophagy/lipophagy, is integral to innate immune responses in macrophages. In particular, cho...

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Detalles Bibliográficos
Autores principales: Hayakawa, Sumio, Tamura, Atsushi, Nikiforov, Nikita, Koike, Hiroyuki, Kudo, Fujimi, Cheng, Yinglan, Miyazaki, Takuro, Kubekina, Marina, Kirichenko, Tatiana V., Orekhov, Alexander N., Yui, Nobuhiko, Manabe, Ichiro, Oishi, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746817/
https://www.ncbi.nlm.nih.gov/pubmed/36509286
http://dx.doi.org/10.1172/jci.insight.138539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746817/
https://www.ncbi.nlm.nih.gov/pubmed/36509286
http://dx.doi.org/10.1172/jci.insight.138539

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