A MUC5B Gene Polymorphism, rs35705950-T, Confers Protective Effects Against COVID-19 Hospitalization but Not Severe Disease or Mortality

RATIONALE: A common MUC5B gene polymorphism, rs35705950-T, is associated with idiopathic pulmonary fibrosis (IPF), but its role in severe acute respiratory syndrome coronavirus 2 infection and disease severity is unclear. OBJECTIVES: To assess whether rs35705950-T confers differential risk for clini...

Descripción completa

Detalles Bibliográficos
Autores principales: Verma, Anurag, Minnier, Jessica, Wan, Emily S., Huffman, Jennifer E., Gao, Lina, Joseph, Jacob, Ho, Yuk-Lam, Wu, Wen-Chih, Cho, Kelly, Gorman, Bryan R., Rajeevan, Nallakkandi, Pyarajan, Saiju, Garcon, Helene, Meigs, James B., Sun, Yan V., Reaven, Peter D., McGeary, John E., Suzuki, Ayako, Gelernter, Joel, Lynch, Julie A., Petersen, Jeffrey M., Zekavat, Seyedeh Maryam, Natarajan, Pradeep, Dalal, Sharvari, Jhala, Darshana N., Arjomandi, Mehrdad, Gatsby, Elise, Lynch, Kristine E., Bonomo, Robert A., Freiberg, Matthew, Pathak, Gita A., Zhou, Jin J., Donskey, Curtis J., Madduri, Ravi K., Wells, Quinn S., Huang, Rose D. L., Polimanti, Renato, Chang, Kyong-Mi, Liao, Katherine P., Tsao, Philip S., Wilson, Peter W. F., Hung, Adriana M., O’Donnell, Christopher J., Gaziano, John M., Hauger, Richard L., Iyengar, Sudha K., Luoh, Shiuh-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746845/
https://www.ncbi.nlm.nih.gov/pubmed/35771531
http://dx.doi.org/10.1164/rccm.202109-2166OC

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746845/
https://www.ncbi.nlm.nih.gov/pubmed/35771531
http://dx.doi.org/10.1164/rccm.202109-2166OC

Ejemplares similares