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A3D database: structure-based predictions of protein aggregation for the human proteome

SUMMARY: Protein aggregation is associated with many human disorders and constitutes a major bottleneck for producing therapeutic proteins. Our knowledge of the human protein structures repertoire has dramatically increased with the recent development of the AlphaFold (AF) deep-learning method. This...

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Detalles Bibliográficos
Autores principales: Badaczewska-Dawid, Aleksandra E, Garcia-Pardo, Javier, Kuriata, Aleksander, Pujols, Jordi, Ventura, Salvador, Kmiecik, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746890/
https://www.ncbi.nlm.nih.gov/pubmed/35445695
http://dx.doi.org/10.1093/bioinformatics/btac215