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Combined proteomics and single cell RNA-sequencing analysis to identify biomarkers of disease diagnosis and disease exacerbation for systemic lupus erythematosus

INTRODUCTION: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease for which there is no cure. Effective diagnosis and precise assessment of disease exacerbation remains a major challenge. METHODS: We performed peripheral blood mononuclear cell (PBMC) proteomics of a discovery cohort,...

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Detalles Bibliográficos
Autores principales: Li, Yixi, Ma, Chiyu, Liao, Shengyou, Qi, Suwen, Meng, Shuhui, Cai, Wanxia, Dai, Weier, Cao, Rui, Dong, Xiangnan, Krämer, Bernhard K., Yun, Chen, Hocher, Berthold, Hong, Xiaoping, Liu, Dongzhou, Tang, Donge, He, Jingquan, Yin, Lianghong, Dai, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746895/
https://www.ncbi.nlm.nih.gov/pubmed/36524113
http://dx.doi.org/10.3389/fimmu.2022.969509