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Suppression of pullulanase-induced cytotoxic T cell response with a dual promoter in GSD IIIa mice

Glycogen debranching enzyme deficiency in glycogen storage disease type III (GSD III) results in excessive glycogen accumulation in multiple tissues, primarily the liver, heart, and skeletal muscle. We recently reported that an adeno-associated virus vector expressing a bacterial debranching enzyme...

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Detalles Bibliográficos
Autores principales: Lim, Jeong-A, Kishnani, Priya S., Sun, Baodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746900/
https://www.ncbi.nlm.nih.gov/pubmed/36264632
http://dx.doi.org/10.1172/jci.insight.152970