Ox40-Cre–mediated deletion of BRD4 reveals an unexpected phenotype of hair follicle stem cells in alopecia

BRD4 is a bromodomain extraterminal domain family member and functions primarily as a chromatin reader regulating genes involved in cell-fate decisions. Here, we bred Brd4(fl/fl) Ox40-Cre mice in which Brd4 was conditionally deleted in OX40-expressing cells to examine the role of BRD4 in regulating...

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Detalles Bibliográficos
Autores principales: Wen, Mou, Ying, Yuanlin, Xiao, Xiang, Arnold, Preston R., Wang, Guangchuan, Chu, Xiufeng, Ghobrial, Rafik M., Li, Xian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746908/
https://www.ncbi.nlm.nih.gov/pubmed/36256455
http://dx.doi.org/10.1172/jci.insight.164534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746908/
https://www.ncbi.nlm.nih.gov/pubmed/36256455
http://dx.doi.org/10.1172/jci.insight.164534

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